Melatonin is produced naturally in the pineal gland of the brain in response to changes in light exposure. Normal melatonin secretion is suppressed by light and stimulated by periods of darkness. Nocturnal secretion of melatonin is at its highest during childhood, and then decreases with age. Studies, including meta-analyses, suggest that supplemental melatonin supports desirable sleep patterns in certain individuals, including the elderly and those who have unusual work hours, such as night shift workers or people traveling across time zones. Melatonin can be taken as a supplement to support these functions by promoting normal levels of melatonin in the body. It plays an important role in regulating the body’s rhythms, equating to the sleep/wake cycle, making it ideal for jet lag. Different research suggests that melatonin supports antioxidant activity, cardiovascular health, and immune function as well. Hormone replacement therapy helps your body maintain melatonin levels.
Not only does melatonin help maintain healthy sleep patterns, it helps antioxidant and immune activities. Studies have shown melatonin plays a role in supporting antioxidant activity, especially sinceintracellular melatonin is concentrated in the mitochondria which is a major site of oxidative metabolism. Melatonin has been found to support extracellular antioxidant activity, support glutathione production, and stimulate production of intracellular antioxidant enzymes—includingsuperoxide dismutases and glutathione peroxidase. It is also suggested that melatonin works on a number of different levels such as its able to scavenge oxygen-based and nitrogen-based free radicals and support the natural response to inflammation by promoting cytokine balance. As a lipophilic molecule, melatonin is able to permeate the lipid portion of low-density lipoprotein (LDL) and support antioxidant activity in cells. Research suggests that melatonin supports blood pressure already in the normal range and overall cardiovascular health.
Lastly, it is suggested that melatonin helps the immune system by supporting T-helper cell function, immune-specific progenitor cell production, cytokine balance, and production of mediators, such as gamma-interferon and immune-supportive interleukins.
Various factors may cause melatonin levels to become low, such as inadequate poor diet, normal aging, insufficient exposure to natural light, exposure to light while sleeping and certain medications. Melatonin may support a healthy immune and stress response. Omega Health & Wellness offers melatonin to support healthy sleep patterns, antioxidant activity, cardiovascular health, and immune function.